1915day.year

Typhoid Mary, the first healthy carrier of disease ever identified in the United States, is put in quarantine for the second time, where she would remain for the rest of her life.

On March 27, 1915, Mary Mallon, known as 'Typhoid Mary', was placed in quarantine for the second time after being identified as an asymptomatic carrier of typhoid fever. She remained isolated for the rest of her life, highlighting early challenges in public health and disease control.
Mary Mallon worked as a cook in New York City when health officials traced multiple typhoid outbreaks to her presence, despite her showing no symptoms. After rigorous investigation, she was confirmed as the first healthy carrier of typhoid fever in the United States. Mallon was first quarantined in 1907 but released under the condition she no longer work in food service. Violating this agreement, she changed her name and continued cooking, leading to further outbreaks. On March 27, 1915, authorities recaptured and quarantined her permanently on North Brother Island. Her case provoked ethical debates over individual rights versus public safety and contributed to the development of modern epidemiological practices.
1915 Typhoid Mary healthy carrier quarantine
1998day.year

The Food and Drug Administration approves Viagra for use as a treatment for erectile dysfunction, the first pill to be approved for this condition in the United States.

The U.S. Food and Drug Administration approves Viagra as the first oral treatment for erectile dysfunction on March 27, 1998. The approval revolutionizes men's health and sparks a cultural phenomenon.
Developed by Pfizer, sildenafil citrate was initially investigated for heart-related chest pain. Clinical trials revealed its unexpected efficacy in treating erectile dysfunction. On approval day, Viagra became the first pill authorized by the FDA for this condition. Doctors rapidly adopted the medication, prescribing it to millions of men worldwide. The drug’s success generated over a billion dollars in yearly sales within just a few years. Viagra’s launch also spurred research into similar treatments for sexual health. Its impact extended beyond medicine, influencing media, advertising, and public discourse.
1998 Food and Drug Administration Viagra erectile dysfunction