1882day.year

Transit of Venus, second and last of the 19th century.

The second and final Transit of Venus of the 19th century occurs.
On December 6, 1882, observers around the world witnessed the Transit of Venus as the planet passed directly between Earth and the Sun. This rare astronomical event allowed scientists to refine measurements of the solar system’s scale using the principle of parallax. Expeditions were dispatched to remote locations to record precise timings of ingress and egress. Data collected during the transit helped improve estimates of the astronomical unit and deepened understanding of planetary motion. The 1882 transit marked the culmination of international scientific collaboration in the 19th century. It would be more than a century before the next Transit of Venus occurred in 2004.
1882 Transit of Venus 19th century
1957day.year

Project Vanguard: A launchpad explosion of Vanguard TV3 thwarts the first United States attempt to launch a satellite into Earth orbit.

On December 6, 1957, the Vanguard TV3 rocket exploded at liftoff, aborting America's first attempt to place a satellite into orbit.
In the early space race, Project Vanguard aimed to demonstrate peaceful scientific exploration. Vanguard TV3 was to carry the first U.S. satellite into Earth orbit on national television. Moments after ignition, the rocket lost thrust and toppled, triggering a spectacular explosion. This public failure dealt a blow to American prestige after the Soviet Union’s Sputnik success. Engineers analyzed the mishap, leading to design improvements for future launches. Lessons learned from Vanguard TV3 paved the way for the successful Explorer 1 mission.
1957 Project Vanguard launchpad Vanguard TV3 satellite
1967day.year

Adrian Kantrowitz performs the first human heart transplant in the United States.

On December 6, 1967, Dr. Adrian Kantrowitz performed the first human heart transplant in the United States at Maimonides Hospital in Brooklyn.
Just days after South Africa’s first transplant, Dr. Kantrowitz led the U.S. effort in pioneering cardiac surgery. The operation took place at Maimonides Hospital, marking a milestone in American medical history. Though the patient survived only briefly, the procedure proved that human heart transplantation was feasible. The surgical team refined techniques for donor matching, immunosuppression, and postoperative care. Their work inspired rapid advancements in transplant medicine across the globe. Today, heart transplantation is a routine life-saving procedure thanks to these early breakthroughs.
1967 Adrian Kantrowitz
1995day.year

The United States Food and Drug Administration approves Saquinavir, the first protease inhibitor to treat HIV/AIDS. Within 2 years of its approval, annual deaths from AIDS in the United States fall from over 50,000 to approximately 18,000.

The FDA approves Saquinavir, the first protease inhibitor for HIV/AIDS treatment.
On December 6, 1995, the U.S. Food and Drug Administration approved Saquinavir, marking the arrival of protease inhibitors in HIV/AIDS therapy. This breakthrough transformed patient outcomes, reducing annual U.S. AIDS deaths from over 50,000 to around 18,000 within two years. Saquinavir targeted a key enzyme in the HIV lifecycle, curbing viral replication. Its approval ushered in combination antiretroviral therapy, turning HIV into a manageable chronic condition. The milestone stands as a triumph of medical research and regulatory collaboration.
1995 Food and Drug Administration Saquinavir protease inhibitor HIV/AIDS
2006day.year

NASA reveals photographs taken by Mars Global Surveyor suggesting the presence of liquid water on Mars.

NASA releases images suggesting liquid water on Mars, reigniting interest in potential extraterrestrial life.
On December 6, 2006, NASA unveiled images from the Mars Global Surveyor spacecraft showing dark streaks on Martian slopes. These features were interpreted as signs of seasonal liquid water flow. The discovery challenged previous assumptions about the planet’s dry environment. Scientists speculated that briny water could persist near the surface during warmer months. This finding influenced future Mars missions, focusing on water detection and astrobiology. The prospect of liquid water revived hopes of discovering past or present microbial life on Mars.
2006 NASA Mars Global Surveyor water on Mars